Flavour Manufacturer Supply Artificial Flavors Alpha-Pinene

• Customization: Available
• CAS No.: 2437-95-8
• Formula: C10h16
• Model NO.: zhishang
• EINECS: 219-445-9
• Type: Synthesis Material Intermediates
• Appearance: Liquid
• Quality: Industrial
• Colour: Colorless
• Certificate: ISO 9001
• Sample: Available
• Packing: 25kg/Drum
• Supply Type: OEM/ODM
• Delivery: 3-5day
• MOQ: 1kg
• Transport Package: 25kg/Drum
• Trademark: ZHISHANG
• Origin: China
• Production Capacity: 50000kg/Mouth

Product Description

Application:
1. Anti-tumor effect ZhangZ et al., in the study of the effect of α-pinene on non-small cell lung cancer, treated α-pinene with paclitaxel to treat A549 cells, and the combination of drugs can increase the effect of paclitaxel in inhibiting tumors. The results show that α-pinene can significantly promote tumor cell apoptosis. This is mainly due to the synergistic effect produced when combined with paclitaxel. Further research mechanisms have shown that when α-pinene and paclitaxel are used in combination, the ratio of cells in G0/G1 phase can be significantly increased, and there are changes in cell morphological characteristics, such as chromatin pyknosis, nuclear fragmentation, etc., to cause The production of tumor cell apoptosis.

2. Antifungal effect: The main components of the cell wall of Candida albicans are chitin, glucose and mannan, the chemical composition of the cell membrane is mainly ergosterol, the nucleic acid is mainly DNA, and a small amount of RNA. The synthesis of these components can lead to the death of bacterial cells. Xia Zhongdi and others found that α-pinene can significantly inhibit the synthesis of chitin and polysaccharides in the cell wall of Candida albicans, the synthesis of ergosterol in the cell membrane, and the synthesis of nucleic acid DNA and ChemicalbookRNA. Among them, the inhibition of the synthesis of ergosterol is more obvious. PichetteA and other studies also found that α-pinene has anti-inflammatory, antibacterial and anti-oxidant effects.

3. Anti-allergic and improving ulcer effects. In the research on the inhibitory effect of α-pinene on allergic rhinitis in mice by NamSY et al., it was found that the expression of IL-4 in spleen lymphocytes decreased, and the IgE, α-TNF, ICAM in the nasal mucosa -1 and macrophage inflammatory protein-2 decreased. The increased eosinophils and mast cells in mice were also significantly reduced after α-pinene treatment. In addition, in the study of the effect of α-pinene on the human mast cell line HMC-1, α-pinene can inhibit the phosphorylated RIP2, IKK-β, NF-κB and caspase-1 activities after sensitization. Therefore, α-pinene is considered an anti-allergic agent. In the study of improving ulcers, the α-pinene extracted from the oil of PinheiroMdeA et al. was used to treat gastric ulcers in mice, and it was found that α-pinene has significant anti-ulcer activity

 

Melting point	-55 °C
Boiling point	155-156 °C(lit.)
density	0.858 g/mL at 25 °C(lit.)
refractive index	n20/D 1.465(lit.)
Fp	90 °F
CAS DataBase Reference	2437-95-8(CAS DataBase Reference)